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The aim of this trial was to investigate whether treatment involving an oxalate-metabolising bacterium (Oxalobacter formigenes) could reduce urinary oxalate excretion in PH patients. Abstract. Patients with primary hyperoxaluria experience kidney stones from a young age and can develop progressive oxalate nephropathy. Progression to kidney failure often develops over a number of years, and is associated with systemic oxalosis, intensive dialysis, and often combined kidney and liver transplantation. Background: Primary hyperoxaluria type 1 (PH1) is a rare monogenic disorder characterized by excessive hepatic production of oxalate leading to recurrent nephrolithiasis, nephrocalcinosis, and progressive kidney damage, often requiring renal replacement therapy (RRT).

Dedicated to improving the care and treatment of, and OxThera has two products in pipeline: • Oxabact™ for the treatment of primary hyperoxaluria, an ultra orphan genetic disease leading to progressive kidney The shareholders in OxThera AB (publ), 556681-5667, are hereby given notice to attend. Extraordinary General Meeting (”EGM”) on 3rd March, Oxabact. Live bacteria. Preclinical. (CDN).

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Oxabact. Live bacteria. Phase III. Invest.

OxThera presenterar fullständiga tvåårsdata för Oxabact ® för

Stockholm - 6 April 2020. OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), ann Primär hyperoxaluri är en sällsynt ärftlig sjukdom som leder till markant förhöjda nivåer av oxalat i plasma och urin. Höga oxalatnivåer resulterar i njurskador, inklusive kristallutfällning av kalciumoxalat i njurar och andra vävnader. Om sjukdomen inte behandlas kan den orsaka njur- och hjärtsvikt och för tidig död. ePHex - An OxThera Clinical Trial in Primary Hyperoxaluria, Stockholm, Sweden.

Patients with primary hyperoxaluria experience kidney stones from a young age and can develop progressive oxalate nephropathy. Progression to kidney failure often develops over a number of years, and is associated with systemic oxalosis, intensive dialysis, and often combined kidney and liver transplantation. STOCKHOLM, Sweden--(BUSINESS WIRE)--OxThera today announced that all 42 patients have been enrolled in their pivotal phase II/III study using Oxabact ™ for the treatment of Primary Hyperoxaluria.
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Phase III. Invest. ePHex - An OxThera Clinical Trial in Primary Hyperoxaluria, MedicalBeautyHouse, Capio Vårdcentral Ringen, AWT Kliniken, Apoteksgruppen, Apoteket Hägern, Coordinate: 59.3516585061, 17.9669809341.

Primary hyperoxaluria is a rare autosomal recessive disorder leading to markedly elevated levels of endogenous oxalate i plasma and urine. High levels of oxalate cause kidney damage, including crystallization of oxalate in tissues and in the kidney.
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Klinisk prövning på Primary Hyperoxaluria: Oxalobacter

OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that the Phase 3 study with Oxabact ® in Primary Hyperoxaluria(PH) is now fully open for recruitment. STOCKHOLM, July 10, 2018 /PRNewswire/ -- OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that the Phase 3 study with Oxabact(R) in Primary Hyperoxaluria (PH) is now fully open for recruitment.All clinics participating in the study are approved by Competent authorities in Europe and US and are initiating patient screening. OxThera currently has two products in its pipeline: Oxabact ® for the treatment of primary hyperoxaluria, and Oxazyme ®, an oxalate decarboxylase, for the treatment of oxalate malabsorption and OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that the Phase 3 study with Oxabact ® in Primary Hyperoxaluria (PH) is now fully open for recruitment.

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OxThera AB - Företagsinformation - Allabolag

OxThera currently has two products in its pipeline: Oxabact® for the treatment of Primary Hyperoxaluria, and Oxazyme®, an oxalate decarboxylase, for dietary hyperoxaluria and prevention of kidney stones OxThera AB, a Stockholm-based privately-held biopharmaceutical companyand leader in the field of microbiome derived biotherapeutics, today announced a poster presentation showing encouraging Oxabact ® efficacy and safety data from the long-term study OC5-OL-01, at the Annual Meeting of the American Society of Nephrology Kidney Week 2018 in San Diego. 2020-04-06 · STOCKHOLM, April 6, 2020 /PRNewswire/ -- OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), announced today that it 2020-04-06 · OxThera Announces Completion of Recruitment in Phase 3 ePHex Study With Oxabact® in Patients With Primary Hyperoxaluria Published: Apr 06, 2020 STOCKHOLM , April 6, 2020 /PRNewswire/ -- OxThera AB , a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), announced today that it has completed enrollment in its Oxabact ePHex phase OxThera AB is a Swedish biotech company developing a new treatment for primary hyperoxaluria - a rare genetic and devastating disease with fatal outcomes. Currently pharmaceutical treatment is not 2019-06-21 · website builders . UF startup OxThera AB, a privately-held Stockholm-based biopharmaceutical company dedicated to improving the lives of people living with Primary Hyperoxaluria, announced that the first patients in a Phase 3 study of Oxabact ® have completed the study and transitioned to an open-label extension part. OxThera AB, a Stockholm -based privately-held biopharmaceutical company, today announced that it has initiated a clinical study in in Primary Hyperoxaluria. Primary Outcome Measures : . Change in pre dialysis plasma oxalate (total plasma oxalate) level during treatment with OC5 compared with baseline.